Smith Drug Store
About Smith Drug Store
Smith Drug Store is a trusted destination for pharmacy, shopping, and health and wellness needs in Spartanburg, SC. Conveniently located at 142 E Main St, the store offers practical services designed to make managing medications and everyday health needs easier.
Customers can choose delivery, in-store pickup, or on-site services based on what works best for them, while the quick-visit planning option makes it convenient to stop in when time matters.
Smith Drug Store also provides medication disposal, giving customers a convenient place to handle unwanted medications responsibly. Accessibility is an important part of the experience, with a wheelchair-accessible car park, entrance, and toilet available for greater ease and comfort during each visit.
Payment options include credit cards, debit cards, NFC mobile payments, and SNAP/EBT, helping accommodate a range of customer preferences.
With a customer rating of 4.50 out of 5 based on 37 reviews, Smith Drug Store has earned strong feedback from the people it serves. Whether you need pharmacy support, medication disposal, delivery, pickup, or on-site services, Smith Drug Store offers a convenient and accessible choice in the Spartanburg community.
For more information, call +1 864-583-4521.
Quality Products
Carefully curated selection
Expert Staff
Friendly, knowledgeable help
Great Value
Competitive pricing always
Happy Customers
Satisfaction guaranteed
What We Offer
Our Collections
Featured Products
Discover our most popular items and best sellers that customers love.
New Arrivals
Fresh inventory arriving regularly. Be the first to see what's new.
Special Offers
Amazing deals and seasonal promotions you won't want to miss.
Our Story
Shop With Confidence
Whether you're looking for something specific or just browsing, our knowledgeable team is here to help you find exactly what you need.
Our Store
Browse our beautiful space
Customer Reviews
What shoppers say about us
dawn licha 3 years ago
Best pharmacy I have ever used. They are super friendly and very knowledgeable
Emily Grace 3 years ago
I’ll never use another pharmacy. They are so friendly & caring. 💞 Thank you Smiths Drugstore!! …
Darlyn Lollis 2 years ago
Been going here for prescriptions for years. Very patient and informative, helped me clear up all types of confusion I had. Excellent service. Highly recommend!
John Hines 3 years ago
I have no words to describe how much better this pharmacy is especially compared to ANY other in town no comparison. I'd drive an hour out of my way, Walgreens etc well they can't even compete. The manager is a good and fair man
Pat Patel 2 years ago
Spoke with Pharmacist. Very knowledgeable and friendly staff. Went out on his way to help out visiting patient in the area and wanting to makes sure his patients were taken care of! Highly Recommend. Dr K and his team!!
Ryan _ 3 years ago
I’d forgotten what it was like to have pharmacists that show that additional level of care and attentiveness before I started using Smith Drug Store. Since I started using Smith last year, it’s been a pleasure. They’re easy to get ahold of on the phone, they work with my schedule, and their level of consultation is excellent.
Anna Johnson 2 years ago
Very thankful for their help finding and filling a prescription at the last minute for my daughter last week. Definitely went beyond what they had to do to help me get it filled before the weekend. Will be having all future scripts filled here.
Tanna Thompson 2 years ago
I love this pharmacy! Great pharmacists & staff. They’re able to order some of my harder-to-get meds that the big box stores can’t seem to get in stock or care to. I really appreciate how they continually go above & beyond!
Meta m Griffin year ago
The pharmacy has given me good advice about allergy and decongestant medications. Other pharmacies don’t have the time to do so. I am considering transferring my prescriptions.
Charles Thornton 2 years ago
Really good folks, the kind that actually cares about you and your needs, they get your meds ready fast, and if they don't have the Rx they will get it the same day or next morning, they make sure you have refill s if not they will call the doctor for you if you want. most of all, great people, friendly, very caring and ready to answer all of your questions with a smile and a thank you.
Frequently Asked Questions
Common questions about Smith Drug Store
- Saturday: 8:30 AM-2 PM
- Sunday: Closed
- Monday: 8:30 AM-6 PM
- Tuesday: 8:30 AM-6 PM
- Wednesday: 8:30 AM-6 PM
- Thursday: 8:30 AM-6 PM
- Friday: 8:30 AM-6 PM
Smith Drug Store is located at 142 E Main St, Spartanburg, SC 29306, United States, Spartanburg, SC, United States.
You can reach Smith Drug Store by calling +1 864-583-4521.
Smith Drug Store has a rating of 4.5 out of 5 based on 37 customer reviews.
Smith Drug Store features the following accessibility: Wheelchair-accessible car park, Wheelchair-accessible entrance, Wheelchair-accessible toilet.
Smith Drug Store features the following from the business: Small Business.
Smith Drug Store features the following service options: Delivery, In-store pick-up, On-site services.
Smith Drug Store features the following offerings: Medication disposal.
Smith Drug Store features the following planning: Quick visit.
Smith Drug Store features the following payments: Credit cards, Debit cards, NFC mobile payments, SNAP/EBT.
Smith Drug Store features the following parking: Free parking lot, Free street parking.
Business Features
Highlights & Amenities
Accessibility
- Wheelchair-accessible car park
- Wheelchair-accessible entrance
- Wheelchair-accessible toilet
From the business
- Small Business
Service options
- Delivery
- In-store pick-up
- On-site services
Offerings
- Medication disposal
Planning
- Quick visit
Payments
- Credit cards
- Debit cards
- NFC mobile payments
- SNAP/EBT
Parking
- Free parking lot
- Free street parking
Visit Our Store
Stop by and see us. We'd love to help you find what you're looking for.
Location
142 E Main St, Spartanburg, SC 29306, United StatesPhone
+1 864-583-4521Store Hours
Get In Touch
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